Fatal Anaphylactic Shock *Rearranged by Editor.

A boy, aged 21 years, had befen suffering from irregular febrile attacks associated with enlarged spleen and liver and progressive anaemia for about nine months. After failure of oral treatment by drugs, the nature of which is not known to the writer, intravenous injection of urea stibamine (Brahmachari) were commenced by a local practitioner. The injections were given at intervals of three or four days and after the fifth, amounting to 0.025 gramme, the boy began to vomit, the face was cyanosed and in a very short time (about a minute) the eyelids and tongue became enormously cedematous. He was given two subcutaneous injections, the nature of which is not known; this brought about rapid amelioration of the symptoms. The doctor in charge of the case having refused to continue the treatment the parents took the boy home. After six or seven weeks the irregular fever and other symptoms returned in a more aggravated form and the boy was taken to another practitioner. He was given 0.025 gramme of urea stibamine intravenously twice a week without any unfavourable signs until, again after the fifth dose, a similar anaphylactic attack occurred. This doctor also refused further treatment.